在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. THBS4 Antibody

THBS4 Antibody

  • 中文名稱：
    THBS4兔多克隆抗體
  • 貨號(hào)：
    CSB-PA562708
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:200
    • Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:200
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    Thbs4 antibody; thrombospondin 4 antibody; thrombospondin 4b antibody; Thrombospondin IV antibody; Thrombospondin-4 antibody; TSP4 antibody; TSP4_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthetic peptide from Human protein at AA range: 551-600
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 純化方式：
    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    IHC,ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC IHC-p:1:50-300
    ELISA 1:10000-20000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions and is involved in various processes including cellular proliferation, migration, adhesion and attachment, inflammatory response to CNS injury, regulation of vascular inflammation and adaptive responses of the heart to pressure overload and in myocardial function and remodeling. Binds to structural extracellular matrix (ECM) proteins and modulates the ECM in response to tissue damage, contributing to cardioprotective and adaptive ECM remodeling. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors and protects myocardium from pressure overload. May contribute to spinal presynaptic hypersensitivity and neuropathic pain states after peripheral nerve injury. May play a role in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury in a NOTCH1-dependent manner.
  • 基因功能參考文獻(xiàn)：
    1. establish a novel molecular mechanism by which miR-148a-3p upregulates Tsp-4 expression in tenocytes to promote angiogenesis by targeting KLF6, which could be helpful for the treatment of tendinopathy in the future PMID: 29807011
    2. Findings indicate that loss of miR-142 results in the over-expression of THBS4, which enhances HCC migration and vascular invasion. PMID: 28177895
    3. the present study demonstrates that THBS4 and lncRNA-THBS4-003 serve a significant role in PCa proliferation and migration via the MMP-9 and p38 MAPK signaling pathway. PMID: 27357608
    4. The THBS4 A387P polymorphism was associated with coronary artery disease in American population. PMID: 25976449
    5. Tsp4 functions as an ECM scaffold at myotendinous junctions, with potential therapeutic uses in tendon strengthening and repair PMID: 24941943
    6. THBS4 expression in breast cancer-associated extracellular matrix contributes to the activated stromal response exhibited during tumour progression PMID: 23942617
    7. the balancing selection target in THBS4 is likely represented by one or more variants that regulate tissue-specific and sex-specific gene expression PMID: 23420636
    8. The results of thid study suggested that injury-induced spinal TSP4 may contribute to spinal presynaptic hypersensitivity and neuropathic pain states. PMID: 22745497
    9. genetic polymorphism predicts cardiovascular risk in postinfarction patients with high HDL cholesterol and C-reactive protein levels PMID: 22011848
    10. Identify THBS4 as a powerful marker for diffuse-type gastric adenocarcinomas and to provide an initial characterization of its expression in the course of this disease. PMID: 21701537
    11. High THBS4 methylation resulting in inactivation of the gene is associated with colorectal cancer. PMID: 20846368
    12. thrombospondin-4 C-terminal peptide has a role in stimulating erythroid cell proliferation PMID: 15474480
    13. Promoter hypermethylation of thrombospondin 4 is associated with cutaneous T-cell lymphoma PMID: 15897551
    14. Homozygosity for thrombospondin-4 1186C (Arg387Pro) variant is a risk factor for myocardial infarction especially in older women. PMID: 16923428
    15. The functional analysis of the rat counterpart. PMID: 7490284

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Endoplasmic reticulum. Sarcoplasmic reticulum. Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
  • 蛋白家族：
    Thrombospondin family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 11788

    OMIM: 600715

    KEGG: hsa:7060

    STRING: 9606.ENSP00000339730

    UniGene: Hs.211426



主站蜘蛛池模板： 久久精品国产亚洲a片高清不卡| 免费香蕉成视频人网站| 2020最新无码国产在线观看| 少妇大叫太大太爽受不了在线观看 | 欧美中日韩免费观看网站| 把插八插露脸对白内射| 国产黑色丝袜在线视频| 色妞色视频一区二区三区四区 | 成人做爰www网站视频下载| 狠狠色婷婷久久综合频道毛片| 天天躁日日躁狠狠躁欧美老妇小说| 色综合色狠狠天天综合色| 国产亚洲精品久久yy5099| 成在人线av无码免费看网站 | 色中色成人导航| 一品二品三品中文字幕| 久久久久人妻一区二区三区vr | 精品久久久久久无码人妻vr| 五月综合激情婷婷六月色窝| 一女被多男玩喷潮视频| 久久精品国产一区二区三区| 青青青国产在线观看免费| 亚洲va中文字幕无码一二三区| 国精产品一品二品国精在线观看| 国语对白做受xxxxx在线中国| 182tv午夜福利在线地址二| 伊人大杳焦在线| 少妇愉情理伦片bd| 丰满少妇被猛烈进入高清播放| 国产午夜精品久久精品电影| 国产饥渴孕妇在线播放| 欧美人与动牲交aⅴ| 国产精品美女一区二区视频 | 国产第一页浮力影院草草| 久久这里精品国产99丫e6| 久久精品中文字幕一区二区三区| 亚洲电影天堂av2017| 欧美精品一产区二产区 | 欧美大片18禁aaa免费视频| 亚洲a∨精品无码一区二区| 久久无码高潮喷水|